T.E.N. PCR Services
Urinary Tract Infections
- 70% UTIs caused by E. coli in past; simple to treat.
- Most commonly diagnosed illness in older adults.
- Now problems with Recurrent and Persistent Infections.
- Development of MDROs and Biofilms have complicated the clinical diagnosis.
- Advanced diagnostics are needed to detect culprit pathogen that may not grow in culture due to Biofilm and identify antibiotic resistance genes.
- We can no longer assume our first or second-line antibiotics will work.
Upper Respiratory Infections
- Acute respiratory infection is a major cause of morbidity and mortality in young, geriatric and immunocompromised patients.
- Rapid antigen tests like the flu and Strept. tests have created a false sense of security among patients and providers – they lack sensitivity and only focus on a single pathogen diagnosis.
- Co-infection is HIGH in Respiratory illness.
- False negatives can lead to a delayed diagnosis and poor clinical outcomes.
Antibiotic Resistance - COMPLICATIONS OF TREATMENT
- Each year in the United States, at least 2 million people acquire infections with bacteria that are resistant to one-or-more of the antibiotics designed to treat those infections. At least 23,000 people die each year as a direct result from these antibiotic-resistant infections. Many more die from other conditions that were complicated by an antibiotic-resistant infection. https://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf.
- In addition, almost 250,000 people each year require hospital care for Clostridium difficile (C. difficile) infections.
- In most of these infections, the use of antibiotics was a major contributing factor leading to the illness. At least 14,000 people die each year in the United States from C. difficile infections. Many of these infections could have been prevented. https://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf
- The use of antibiotics is the SINGLE MOST IMPORTANT FACTOR leading to antibiotic resistance around the world.
- Antibiotics are among the MOST COMMONLY PRESCRIBED DRUG in human medicine.
- Up to 50% of all the antibiotics prescribed for people ARE NOT NEEDED or are not optimally effective as prescribed. https://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf