Because precision is important.
TEN Healthcare is quickly becoming the new gold standard in pathogen identification. TEN utilizes real-time PCR technology. This allows for:
- Greater sensitivity than culture
- 12-24 hours turnaround time
- Viable specimen is NOT required, NOT affected by temperature, and NO transport medium is required
Because your clinical needs are the priority.
Complications of Treatment:
- Each year in the United States, at least 2 million people acquire infections with bacteria that are resistant to one of more of the antibiotics designed to treat those infections. At least 23,000 people die each year as a direct result from these antibiotic-resistant infections. Many more die from other conditions that were complicated by an antibiotic-resistant infections.
- In addition, almost 20,000 people each year require hospital care for Clostridium difficile (C. difficile) infections. In most of these infections, the use of antibiotics was a major contributing factor leading to the illness. At least 14,000 people die each year in the United States from C. difficile infections. Many of those infections could have been prevented.
- The use of antibiotics is the SINGLE MOST IMPORTANT FACTOR leading to antibiotic resistance around the world.
- Antibiotics are among the MOST COMMONLY PRESCRIBED DRUG in human medicine.
- Up to 50% of all antibiotics prescribed for people ARE NOTE NEEDED or are not optimally effective as prescribed.
- TEN Healthcare utilizes Real-Time PCR via Quantstudio technology to precisely identify pathogens by their RNA or DNA sequence.
- PCR (Polymerase Chain Reaction) is a molecular technique that was used to sequence the 1st human genome.
- Many advancements in the PCR technology since then that has made it efficient and affordable.
- Quickly becoming the new gold standard in pathogen identification.
- Molecular testing for pathogen identification can replace the conventional method of culture and sensitivity.
- The differences in techniques:
- Culture & Sensitivity requires sending a viable sample to a microbiology lab that is set in an agar medium and incubated to promote growth of the bacteria.
- Molecular testing via PCR requires sending a sample to a molecular lab where the DNA or RNA of the pathogen is extracted and amplified.
|Sensitivity||Fair||3-5x greater sensitivity than culture|
|Turn-Around-Time||2-5 days after lab arrival (bacteria growth rate dependent)||12-24 hours after lab arrival|
|Vulnerability to Transport||Viable specimen needed; sensitive to temperatures and drying; needs special transport medium||Viable specimen NOT required; not affected by temperatures; no transport medium required|
|Strain Typing||Requires 2nd step||Often incorporated in initial|
TEN Healthcare Molecular Testing Advantages
- Rapid & accurate diagnosis
- Noninvasive collection (swab)
- Detection of multiple pathogens at once
- Sensitivity unaffected by concomitant antibiotic use
- Reduce unnecessary antibiotic administration, adverse events and costs
- Decrease the spread of acquired infections
- Ability to test for antibiotic resistance genes